http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112748241-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbef0bcc2f27e637c3dfb1356bb2c5d4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-535 |
filingDate | 2019-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0048dea290db8c8714723d92f46c6b0f |
publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112748241-A |
titleOfInvention | Protein chip for detecting I-type osteoporosis and manufacturing method and application thereof |
abstract | The invention belongs to the field of biological detection, and particularly belongs to a protein chip for detecting I-type osteoporosis and a manufacturing method and application thereof. The invention analyzes differential protein in the serum and peripheral blood mononuclear cells of a patient with type I osteoporosis based on iTRAQ protein quantitative omics. The iTRAQ protein quantitative technology has high sensitivity, can simultaneously execute the detection of a plurality of samples, and avoids the difference between groups among a plurality of mass spectra. Therefore, candidate differential proteins in type I osteoporosis patients screened by the present invention are highly reliable. The method has the advantages of extremely small required sample amount, high signal-to-noise ratio, high accuracy and high sensitivity; the method is rapid, miniaturized and automatic, and can carry out quantitative detection through a standard curve; therefore, the product developed by the invention can greatly improve the accuracy and efficiency of clinical diagnosis of the type I osteoporosis patients, and has strong application innovativeness and very important clinical research significance. |
priorityDate | 2019-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 308.