http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112745385-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 |
filingDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112745385-B |
titleOfInvention | Recombinant humanized collagen, industrial preparation method and product application thereof |
abstract | The invention relates to a recombinant humanized collagen and a preparation method and application thereof. The amino acid sequence of the humanized collagen (rHLC) is shown as SEQ ID NO: 1, the sequence is taken as a core unit to be connected in series by 3-25 repeats to form a series of humanized collagen molecules with different molecular weights. The rHLC molecular sequence is derived from human type I collagen, has great water solubility and hydrophilicity, simultaneously has good moisture retention, hygroscopicity and biocompatibility, and has obvious proliferation promoting effect; can be expressed efficiently in an escherichia coli host; the fermentation process culture medium has low cost, clear components, short fermentation period, simple control and easy process amplification; the purification method has the advantages of simple operation, low cost, good effect and stable process, the purity of purified products, endotoxin, HCP, DNA residue and the like can meet medicinal standards, the production process can meet the requirement of industrialized production, and the method can be applied to medical and cosmetic cosmetics or functional cosmetics. |
priorityDate | 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.