http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112745257-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 |
| filingDate | 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112745257-B |
| titleOfInvention | (1R) -phenylamino- (2S) -2-aryl-2-nitrogen heteroaryl cyclopentane and preparation method and application thereof |
| abstract | The invention discloses a (1) R ) -phenylamino- (2) S ) Dispersing N-phenylcyclopropane, 2- (1-aryl vinyl) azaarene, photosensitizer DPZ and chiral catalyst BA in an organic solvent, degassing at the temperature of not higher than-78 ℃, placing the mixture in a protective atmosphere at the temperature of 20-30 ℃, irradiating the mixture by using a 3-10W blue lamp for reacting for 8-12 hours, and separating and purifying after the reaction is finished to obtain (1) R ) -phenylamino- (2) S ) -2-aryl-2-azaheteroaryl cyclopentane. The enantiomeric excess of the target product obtained by the method is more than 70%, the yield is more than 80%, the reaction condition is mild, and no pollution is caused. |
| priorityDate | 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.