http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112716953-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
filingDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112716953-B |
titleOfInvention | Application of CDN1163 in preparing medicine for relieving or treating neuropathic pain |
abstract | The CDN1163 can act on one or more of neuropathic pain including central neuropathic pain and peripheral neuropathic pain, improve mechanical pain sensitivity and thermal pain sensitivity caused by chronic sciatic nerve compression injury of rats, improve neuron shrinkage and astrocyte activation of 5 dorsal root ganglia of lumbar intervertebral foramen, inhibit neuron excitability increase of 4-6 dorsal root ganglia of lumbar intervertebral foramen, effectively relieve neuropathic pain symptoms, remarkably reverse mechanical hyperalgesia and thermal hyperalgesia by repeated injection, have no tolerance signs, maintain treatment effect after stopping medicine injection, and be applied to preparation of medicines for relieving or treating neuropathic pain which lasts for a long time and is difficult to treat. |
priorityDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.