| abstract |
The transdermal amisulpride patch comprises a drug-loaded layer, a back lining layer and an anti-sticking layer, wherein the drug-loaded layer consists of amisulpride, a penetration enhancer and a pressure-sensitive adhesive matrix. The weight percentage content of amisulpride in the drug-carrying layer is 3-5%. The weight percentage content of the penetration enhancer in the drug-loaded layer is 4% -6%, and the penetration enhancer is propylene glycol, oleic acid and menthol in a weight ratio of 10: 1-3: 0.1-0.2. The pressure-sensitive adhesive matrix is a hot-melt pressure-sensitive adhesive matrix. |