| abstract |
The present invention provides a 5-membered heteroaryl-substituted pyrazine derivative having a chemical structure represented by formula |, a pharmaceutical preparation comprising the same, and its application in a medicine for treating or preventing osteoporosis, The compound of the present invention can significantly inhibit the proliferation of osteoclasts, has excellent activity, can increase the size of fracture force, and increase the content of bone calcium and bone phosphorus, and can be used as a new structural drug for osteoporosis for further in-depth research. Research and Development. |