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filingDate 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112697921-B
titleOfInvention How to detect maprotiline
abstract The present invention provides a method for detecting maprotiline, comprising: preparing at least three standard solutions with maprotiline and an internal standard substance in concentrations; detecting each standard solution separately by using a liquid chromatograph under preset detection conditions , obtain the first detection result corresponding to each standard solution; fit the standard curve equation of maprotiline according to each first detection result, the concentration of maprotiline in the standard solution and the concentration of the internal standard substance; The sample is centrifuged, and the first supernatant after centrifugation is taken; the internal standard substance and protein precipitation reagent are added to the first supernatant, and the protein is precipitated after vortex mixing to obtain the sample to be tested; using a liquid chromatograph Detect the sample to be tested under the detection conditions to obtain a second detection result; based on the standard curve equation and the second detection result, obtain the concentration of maprotiline in the sample to be tested. This solution can shorten the sample detection time.
priorityDate 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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