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filingDate 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc74805253564404d513887a58fad575
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publicationDate 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112697860-A
titleOfInvention Tumor cell exosomes and nucleic acid detection chip and method for making and detecting the same
abstract Provided is a tumor cell exosome and a nucleic acid detection chip thereof, comprising a glass substrate (1) and a PDMS sheet (2) attached to each other, wherein the PDMS sheet (2) is provided with a first through hole (3) and a second through hole ( 4), the third through hole (5), the pit (6), the initial flow slot (7), the first flow slot (8), and the second flow slot (9) are connected in sequence; the pit (6) forms a TEX capture detection The third through hole (5) forms the microRNA capture and detection area; the corresponding areas of the glass substrate (1) are respectively sputtered with a three-electrode system for capturing and detecting TEX and microRNA; the first flow channel section, the second flow channel section The first valve and the second valve that can close the flow channel section are arranged above; the tumor cell exosome and its nucleic acid detection function are integrated into one; the invention also provides a manufacturing method and a detection method of such a chip.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113552041-A
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Total number of triples: 38.