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filingDate 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04389387faae747166638b2323e201f1
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publicationDate 2021-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112695083-A
titleOfInvention A kind of nucleic acid composition and kit for detecting hypertension drug gene polymorphism
abstract The present application discloses a nucleic acid composition and a kit for detecting gene polymorphisms of drugs for hypertension, which belong to the technical field of gene detection. The nucleic acid composition includes the 1165G>C site for detecting ADRB1 gene, the 100C>T site for the CYP2D6*10 gene, the 1075A>C site for the CYP2C9*3 gene, the 6986A>G site for the CYP3A5*3 gene, and the 1166A for the AGTR1 gene. >C site, NPPA gene 2238T>C site, ACE(I/D) gene, MTHFR gene 677C>T site, ApoE gene 388T>C site and ApoE gene 526C>T site upstream and downstream primers and probe. The kit comprising the above primers and probes can simultaneously perform real-time fluorescent detection on the above 10 mutation sites, with good specificity, high sensitivity, short detection period, high detection efficiency and low detection cost.
priorityDate 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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