http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112684182-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26 |
| filingDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112684182-B |
| titleOfInvention | Immunosensor system for detecting PD-L1 in non-disease diagnosis |
| abstract | The invention discloses an immunosensor system for detecting PD-L1 in non-disease diagnosis, which comprises diamine guest molecules and pSC 4 AuNPs, attached pSC 4 The chip, the PD-L1 antibody and the Homing Peptide functionalized silver-coated magnetic nanoparticles, wherein diamine guest molecules and pSC 4 After AuNPs ligation, pSC was attached 4 The surface of the chip is self-assembled to construct 3D-AuNPs serving as a sensitization layer, PD-L1 antibody is adsorbed on the sensitization layer, and the functionalized magnetic silver-coated nanoparticles of the Homing Peptide are added into the chip with pSC after reacting with the analyte 4 Thereby specifically recognizing the PD-L1 antibody. The 3D-AuNPs are used as an antibody fixing substrate, the antibody can be fixed in an oriented mode by the supermolecular layer, based on the mechanism action of intracellular peptides, the immunosensor can be constructed by replacing the antibody, and the cost is low. |
| priorityDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.