http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112680410-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112680410-B |
| titleOfInvention | A method for inducing pluripotent stem cells to differentiate and culture cardiac fibroblasts and their culture medium |
| abstract | The invention discloses a method for inducing pluripotent stem cells to differentiate and culture cardiac fibroblasts and a culture medium thereof. The method comprises: using a culture medium for promoting cardiac mesoderm progenitor cells to conduct directional differentiation and culturing of induced pluripotent stem cells to obtain cardiac mesoderm Progenitor cells; further differentiated and cultured with the second heart field progenitor cell culture medium to obtain the second heart field progenitor cells; finally, the purified mature cardiac fibroblasts were obtained by culturing with the cardiac fibroblast culture medium. In the culturing method of the present invention, the material is convenient to obtain, the culturing time is short, and the differentiation efficiency is high, and the obtained cardiac fibroblasts can be used for clinical treatment of heart failure, as well as in vitro disease modeling research, drug screening and other biomedical applications. |
| priorityDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.