http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112680405-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
filingDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112680405-B |
titleOfInvention | Human endoderm differentiation medium and culture method |
abstract | The invention provides a culture medium for inducing differentiation of human endoderm, which consists of the following culture medium A and culture medium B: medium a consisted of the following components: DMEM/F12 medium, vitamin C and ChIR 99021; medium B consisted of the following components: DMEM/F12 medium, vitamin C and LDN-193189. The endoderm obtained by the induced differentiation of the invention can be differentiated into liver cells, pancreatic precursor cells and lung precursor cells in vitro, and can be differentiated into lung and gastrointestinal tract epithelial cells in an in vivo teratoma experiment, which shows that the endoderm differentiated by the method has the potential of being divided into liver, lung and pancreas. |
priorityDate | 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 393.