http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112675154-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H3-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-43 |
| filingDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112675154-B |
| titleOfInvention | A dual-response drug-releasing MOFs@IBU nanofiber transdermal sustained-release material and its preparation method and application |
| abstract | The invention provides a MOFs@IBU nanofiber transdermal sustained-release material with dual-response drug release and a preparation method and application thereof. The preparation method of the sustained-release material comprises the steps of: mixing ligand 4, 4'-((4-(4H-1,2,4-triazol-4-yl)benzene)azodioyl)dibenzoic acid, Zinc nitrate and ibuprofen were dissolved in a mixed solvent of water and N,N-dimethylformamide, and diethanolamine (DEA) was added to mix them evenly. The reaction was allowed to stand at room temperature for 20-30h, and the MOFs were obtained by centrifugation, washing and drying. @IBU; Dissolve polyacrylonitrile in N,N-dimethylformamide (DMF), add MOFs@IBU, mix and disperse uniformly to obtain spinning solution; then electrospin and dry to obtain. The nanofiber membrane obtained by the invention has the drug release capability of dual response of pH and temperature; the preparation process is simple, the energy consumption is low, the structure of the drug-carrying system is easy to control, and the cost is low. |
| priorityDate | 2020-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.