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filingDate 2014-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08ae2fee9f2b4b19598508a834f67b3b
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publicationDate 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112674861-A
titleOfInvention System and method for determining lesion depth using fluorescence imaging
abstract The present invention relates to a system and method for determining lesion depth using fluorescence imaging. Systems, catheters, and methods are provided for treating Atrial Fibrillation (AF) configured to irradiate cardiac tissue having a lesion site; obtaining mitochondrial Nicotinamide Adenine Dinucleotide Hydrogen (NADH) fluorescence intensity from the irradiated heart tissue along a first line across the lesion site; creating a 2-dimensional (2D) map of the depth of the lesion site along the first line based on the NADH fluorescence intensity; and determining from the 2D map a depth of the lesion site at a selected point along the first line, wherein a lower NADH fluorescence intensity corresponds to a greater depth in the lesion site and a higher NADH fluorescence intensity corresponds to non-ablated tissue. This process can be repeated to create a 3-dimensional map of the depth of the lesion.
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