| abstract |
An apparatus includes a flow cell body, a plurality of electrodes, an integrated circuit, and an imaging assembly. The flow cell body defines one or more flow channels and a plurality of wells. Each flow channel is configured to receive fluid flow. Each well is fluidly coupled with a corresponding flow channel. Each well is configured to contain at least one polynucleotide. Each electrode is located in a corresponding well of the plurality of wells. The electrodes are operable to effect writing of polynucleotides in the corresponding wells. The integrated circuit is operable to drive selective deposition or activation of selected nucleotides for attachment to polynucleotides in the wells, thereby producing polynucleotides in the wells representing machine written data. The imaging component is operable to capture images indicative of one or more nucleotides in the polynucleotide. |