| abstract |
The invention discloses an organic conjugated polymer photothermal reagent, nanoparticle, preparation method and application for treating malignant melanoma. The structure of the organic conjugated polymer photothermal reagent for treating malignant melanoma is shown in formula (I). The organic conjugated polymer for treating malignant melanoma of the present invention is prepared by co-precipitation method with amphiphilic compound to prepare nanoparticles, which has good solubility in water environment and excellent biocompatibility; , easy to enter cells; has excellent photostability and chemical properties, and photothermal conversion efficiency, good efficacy in photothermal therapy for melanoma (B16) cells, less side effects, and has the prospect of practical application. |