http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112656934-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40444fc31635efea788661c00e8b1582 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcdd12eb0fb85995a3876ac90a848cbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7adef2812de670826c93a7614b28fbbd |
publicationDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112656934-A |
titleOfInvention | Application of polypeptide AT03 in the treatment of primary biliary cholangitis |
abstract | The invention discloses the application of a polypeptide AT03 in medicine for treating primary biliary cholangitis. The amino acid sequence of the polypeptide AT03 is: Val-His-Val-Val-R 1 ; wherein, R 1 =-NH 2 . After a large number of experimental studies, the present invention proves that the polypeptide AT03 has a therapeutic effect on the cholestatic liver cirrhosis model of common bile duct ligation rats, which is specifically manifested in that it can improve liver cholestasis, intrahepatic biliary obstruction, liver cell damage and liver tissue fibrosis The invention can be applied to the preparation of medicines for the treatment of primary biliary cholangitis. |
priorityDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.