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filingDate 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112618800-B
titleOfInvention Mandibular condyle osteochondral repair scaffold material and preparation method thereof
abstract The invention provides a mandible condylar process osteochondral repair scaffold material and a preparation method thereof, the scaffold material consists of a cartilage surface layer, a cartilage deep layer and a bone layer, wherein the cartilage surface layer consists of composite hydrogel of cross-linked sulfhydryl-hyaluronic acid and type I collagen and bone marrow mesenchymal stem cells distributed in the composite hydrogel, the cartilage deep layer consists of composite hydrogel of cross-linked sulfhydryl-hyaluronic acid and type I collagen and cartilage cells distributed in the composite hydrogel, the bone layer is porous biphase calcium phosphate ceramic, and the cartilage deep layer is positioned between the cartilage surface layer and the bone layer and in a porous structure of the bone layer to connect the cartilage surface layer and the bone layer into a whole. In vivo experiments prove that the scaffold material has excellent repair capability on the cartilage defect of the mandibular condyle, can solve the problems that the existing method and material for treating the cartilage defect of the mandibular condyle cannot repair the cartilage defect of the mandibular condyle, and provides new possibility for the treatment of the cartilage defect of the mandibular condyle.
priorityDate 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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