http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112618797-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 |
| filingDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112618797-B |
| titleOfInvention | Preparation method of a specific demineralized extracellular matrix scaffold of cross-linked antibiotics |
| abstract | The invention discloses a preparation method of a cross-linked antibiotic specific demineralized extracellular matrix scaffold, which belongs to the technical field of bone infection treatment. The invention discloses a preparation method of a specific demineralized extracellular matrix scaffold of cross-linked antibiotics. The specific demineralized and decellularized cancellous bone extracellular matrix scaffold (SDECM) is used as a substrate, and the antibiotic is electrostatically adsorbed and chemically adsorbed. Cross-linking two forms of composite drug loading, releasing antibiotics through rapid pH response and accompanying material degradation in an acidic environment, anti-infection through antibiotics and promoting repair through SDECM, so as to achieve pH-sensitive drug release in an acidic environment in the early stage of infection Rapid sterilization, sustained sterilization by slow release of drugs in the mid-late physiological environment, and permanent sterilization ability to prevent infection recurrence in the absence of infection provide new ideas and tools for the antibacterial and repairing treatment of bone infections. |
| priorityDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.