| abstract |
The invention provides a hemostatic sponge for gastroenterology and a preparation method thereof. The hemostatic sponge includes at least one biodegradable hydrophilic sponge layer in contact with the wound, the hydrophilicity gradually increases from the outer edge to the center thereof, and the water contact angle of the outermost edge is greater than or equal to 90°. In addition, the positive charge content of the biodegradable hydrophilic sponge layer increases sequentially from its outer edge to its center. This arrangement forms a wicking effect, which helps to accelerate the adsorption of the tissue fluid in the blood by the hemostatic sponge, thereby accelerating the blood to form a thrombus to block the wound, and can effectively prevent blood leakage and seepage, and improve the hemostasis effect. The positive charge in the center of the hemostatic sponge is the most, which is helpful for the rapid adhesion and aggregation of platelets in the blood, and further improves the hemostatic effect. |