http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112618561-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf37dac778fdba643628dc86519f4896 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7056 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056 |
| filingDate | 2021-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a85a643a564ae427a2b8150f025f95b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b21e03763e5cfc03564eb4958e293ebd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73e754b0f4c055e64b7d52b8310bcef3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_730eacf1729d219e0f6d732eeaaf679a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8517afd63b386af96a3b2a949270acd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_248a57d0545e16c18d1503f6b9b9fbfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65e2b59bf942456519c77d386de06cdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_828cbac5e5588eb539ac5dfbc85ca16d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cccb9113ab60382c6f50b8112422f29 |
| publicationDate | 2021-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112618561-A |
| titleOfInvention | Application of Ribavirin in the Preparation of Drugs for Inhibiting Bacterial Quorum Sensing |
| abstract | The invention discloses an application of ribavirin in preparing a drug for inhibiting bacterial quorum sensing. It can effectively inhibit the quorum sensing system of Gram-negative pathogen Pseudomonas aeruginosa . It solves the problems that traditional antibiotics treat multi-drug-resistant pathogen-related infections with few effective drugs, long cycle, and easy recurrence of the disease. The invention includes the following characteristics: it can simultaneously inhibit the expression of three main control genes lasR , rhlR , pqsR and their downstream functional genes of the pseudomonas aeruginosa quorum sensing system, and can significantly inhibit the bacterial toxicity controlled by the pseudomonas aeruginosa quorum sensing system Synthesis of force factor, relieve symptoms of infection. The invention can be used for diseases that require long-term treatment such as multidrug-resistant Gram-negative bacteria represented by Pseudomonas aeruginosa, and is not easy to produce drug resistance. |
| priorityDate | 2021-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.