http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112608376-B

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10
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filingDate 2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112608376-B
titleOfInvention Preparation method of active peptide Apelin
abstract The invention relates to a preparation method of an active peptide Apelin, which comprises the step of connecting 2- (4-chlorphenyl) -2, 2-difluoroacetic acid by a solid phase synthesis method after the Apelin is prepared by the solid phase synthesis method. The active peptide Apelin (2- (4-chlorphenyl) -2, 2-difluoroacetic acid-QRPRLSHKGPMPF) is obtained by a solid phase synthesis method, and the activity of the active peptide Apelin obtained based on the method can be further improved while the half-life period is prolonged.
priorityDate 2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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