http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112608267-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-267 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267 |
| filingDate | 2020-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112608267-B |
| titleOfInvention | A kind of synthetic method of 4-phenyl-2-pyrrolidone |
| abstract | The invention discloses a method for synthesizing 4-phenyl-2-pyrrolidone, which is obtained by using diethyl malonate and 2-nitro-1-acetophenone as raw materials through a condensation reaction with a strong Lewis base. Body 1, in an organic solvent, under palladium-carbon catalytic hydrogenation, obtains intermediate 3 (3-methoxy carboxyl-4-phenyl-2-pyrrolidone), and finally obtains by decarboxylation reaction under organic solvent alkaline conditions The final 4-phenyl-2-pyrrolidone. In addition, 4-phenyl-2-pyrrolidone can also be prepared by one-step Falk alkylation reaction of pyrrolidone and halobenzene. The method of the present invention has the characteristics of easy availability of raw materials, simple reaction conditions and high yield. |
| priorityDate | 2020-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.