| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd4820206d445047cebc73581ee3fa2f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C249-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C251-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate |
2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d2ef2c18e8fc0f853cfa1567d9cfba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5197d4ef381068f5d84e22bb2b062670
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f3f5b4a3532aac13d243742e2dd6d25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3f4b9225511eb53aaa44310fbd0317b |
| publicationDate |
2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112608252-A |
| titleOfInvention |
A kind of 4-nitroaniline derivative and its synthetic method and application |
| abstract |
The invention discloses a 4-nitroaniline derivative, a synthesis method and application thereof, which are obtained by reacting 4-nitro-o-phenylenediamine and 2,4-dichlorobenzaldehyde in an organic solvent under heating conditions. Applicants' experiments show that the compound can inhibit the proliferation of primary airway smooth cells in chronic obstructive pulmonary disease, reduce the progression of pulmonary hypertension and reduce the progression of pulmonary fibrosis. The structure of the 4-nitroaniline derivative of the present invention is shown in the following formula (I): |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113750089-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113750089-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115154466-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115154466-B |
| priorityDate |
2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |