http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112592376-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112592376-B |
| titleOfInvention | A method for the preparation of mannose-containing derivatives that can be used for post-polymerization modification by double click chemistry |
| abstract | The invention relates to a method for preparing a mannose-containing derivative which can be used for post-polymerization modification by combining double click chemistry. First, under the action of propargyl bromide and acryloyl chloride, respectively, a Williamson-forming ether reaction is used to prepare a mannose-containing derivative. Compounds with terminal alkynes and terminal alkenes. Then, the terminal alkene and the mercapto compound undergo a mercapto-ene addition reaction, and the terminal alkyne and the acetyl-protected α-D-mannopyranosyl azide undergo a CuAAC reaction. Compared with the prior art, the present invention successfully combines thiol substances of different structures with α-D-mannopyranosyl azide through the combined method of mercapto-ene addition reaction and GuAAC to prepare A mannose-containing derivative that can be used for post-polymerization modification is developed. The synthesis method is stable and efficient, and provides a considerable way for obtaining sugar-containing homopolymers with controllable molecular weight and narrow molecular weight distribution in the later stage. |
| priorityDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.