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filingDate 2020-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112587724-B
titleOfInvention Low-swelling-rate high-molecular medical hydrogel and preparation method thereof
abstract The invention belongs to the technical field of medical hydrogel preparation, and provides a low-swelling-rate high-molecular medical hydrogel and a preparation method thereof; the method comprises the following steps: (1) uniformly stirring carboxylated bacterial cellulose, N '-diisopropyl carbodiimide and 2, 2' -dithiodiethanol diacrylate to obtain a uniform viscous solution; (2) adding photoinitiator benzoin ethyl ether into the viscous solution, irradiating under an ultraviolet high-pressure mercury lamp for radiation polymerization, and processing at 60-70 ℃ for 1-3h after lamp is turned off to obtain crude gel; (3) and standing and washing the crude gel at room temperature to obtain the low-swelling-rate polymer medical hydrogel. The obtained hydrogel has low swelling rate and good biocompatibility and can be used for narrow and small parts of organisms.
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