http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112587556-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-17 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K125-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2020-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112587556-B |
| titleOfInvention | Ephedrine extract, preparation method and use |
| abstract | The invention discloses an ephedrine alcohol extract, a preparation method and an application. The ephedrine alcohol extract is an active site for inhibiting the interaction of the coronavirus Spike-ACE2 protein, and the active site can not only inhibit the interaction between the coronavirus Spike protein and the ACE2 protein, IC 50 <100μg/ml, and can promote the dissociation of Spike-ACE2 complex. It can effectively inhibit the invasion of the novel coronavirus SARS‑CoV‑2 pseudovirus at the cellular level, with IC 50 <100μg/ml. It is shown that the active part of ephedra has a very positive effect on the preparation of medicines for the treatment and/or prevention of coronavirus infection. |
| priorityDate | 2020-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.