| abstract |
Anti-BCMA antibodies, antigen-binding fragments thereof, and medical uses thereof are provided. Further, provided are chimeric antibodies, humanized antibodies comprising the CDR regions of the anti-BCMA antibody, and pharmaceutical compositions comprising the anti-BCMA antibodies or antigen-binding fragments thereof, and their use as anti-cancer drugs and treatment of autoimmune diseases. use. In particular, a humanized anti-BCMA antibody is provided, and its use in the manufacture of a medicament for the treatment of BCMA-mediated diseases or disorders and in disease detection and diagnosis. |