http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112575021-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K10-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L29-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01026 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-125 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K10-18 |
filingDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112575021-B |
titleOfInvention | A method of producing riboflavin |
abstract | The invention belongs to the field of microbial fermentation and discloses a method for producing riboflavin. The method for producing riboflavin according to the present invention includes a method for constructing a riboflavin-producing strain, and a method for producing riboflavin by fermentation using the constructed strain. The Bacillus subtilis of the present invention is a Bacillus subtilis strain with at least one gene locus mutated in purR, ribR, ribC or pyrE. The Bacillus subtilis strain obtained by mutating at least one gene locus of purR, ribR, ribC or pyrE significantly increases the accumulation of riboflavin under the fermentation conditions disclosed in the present invention. The Bacillus subtilis of the present invention is a high-producing strain of riboflavin, and the riboflavin produced is significantly increased, laying a foundation for the industrial production of riboflavin. |
priorityDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 815.