http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574343-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F120-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F120-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-44 |
| filingDate | 2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112574343-B |
| titleOfInvention | Cationic polymer with hypoxia response and preparation method and application thereof |
| abstract | The invention discloses an anoxic-responsive cationic polymer, a preparation method and application thereof, wherein the cationic polymer has a structure shown in a formula (I), and is obtained by quaternizing 4-nitrobenzyl bromide or 4-nitrobenzyl chloride and polymer PDEA. The cationic polymer provided by the invention has a large amount of positive charges, can wrap DNA well, can change charges under an anoxic condition in tumor cells after entering the tumor cells, and quickly releases the DNA for transfection, and has the characteristics of high efficiency and low toxicity, and good application prospect. |
| priorityDate | 2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.