http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574326-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0009 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-02 |
| filingDate | 2020-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112574326-B |
| titleOfInvention | Rhizoma gastrodiae macromolecule linear straight-chain glucan and preparation method and application thereof |
| abstract | The invention discloses a gastrodia elata macromolecule linear straight-chain glucan and a preparation method and application thereof, and belongs to the field of traditional Chinese pharmacology. The invention dries and crushes the tuber of the gastrodia tuber and degreases the tuber by ethanol. Extracting at room temperature, centrifuging the extractive solution, concentrating, precipitating with ethanol, dissolving precipitate, dialyzing with dialysis bag with molecular weight cutoff of 8000-14000Da, concentrating the dialysate, and separating and purifying with ion exchange resin and gel exclusion chromatography to obtain rhizoma Gastrodiae linear dextran. The polysaccharide is composed of glucose only, is alpha-D-1, 4 connected homopolyglucan, and is a novel glucan. When the concentration is 400 mu g/mL, the compound can obviously promote the proliferation of macrophages, enhance the phagocytic capacity of the macrophages, promote the macrophages to release NO and cytokines TNF-alpha and IL-6, and enhance the immunity of organisms. |
| priorityDate | 2020-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.