http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112569214-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa285faaa918feaad8237cb1f259cec9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48d96269052eaae2008fd8cb63f887fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_997a5cba08fed64b0bd9d5e39f823b3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7395b41df4000e1a508c4bbb52508f1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f05dc8991ab6b5fa39b8d389b8e16b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12b5f8ef41e0c8fc38fdb67bf5237f7e |
publicationDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112569214-A |
titleOfInvention | Application of diallyl sulfide in the preparation of drugs for preventing and/or treating liver fibrosis and liver cancer |
abstract | The invention provides the application of diallyl sulfide in the preparation of medicines for preventing and/or treating liver fibrosis and liver cancer, and belongs to the technical field of medicine. For the first time, the present invention proves that DAS can significantly improve the symptoms of liver fibrosis and hepatocellular carcinoma, and the specific performance is that it can significantly reduce the proliferation of collagen fibers in the liver of mice, reduce the atypia of liver tumor cells, significantly reduce the cancerous area of liver cells, and tend to the hepatic lobule structure. The liver cells are arranged regularly and neatly, and the number of nodules on the liver surface is reduced. From the perspective of biochemical indicators, DAS can significantly reduce the elevation of ALT, AST, γ-GT and AFP activities caused by liver fibrosis and liver cancer, and there is a certain dose-dependent relationship. The invention lays a foundation for the further development and utilization of DAS as a raw material of natural medicines, especially as a raw material for preventing and/or treating liver diseases such as liver fibrosis and liver cancer. |
priorityDate | 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.