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filingDate 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa285faaa918feaad8237cb1f259cec9
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publicationDate 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112569214-A
titleOfInvention Application of diallyl sulfide in the preparation of drugs for preventing and/or treating liver fibrosis and liver cancer
abstract The invention provides the application of diallyl sulfide in the preparation of medicines for preventing and/or treating liver fibrosis and liver cancer, and belongs to the technical field of medicine. For the first time, the present invention proves that DAS can significantly improve the symptoms of liver fibrosis and hepatocellular carcinoma, and the specific performance is that it can significantly reduce the proliferation of collagen fibers in the liver of mice, reduce the atypia of liver tumor cells, significantly reduce the cancerous area of liver cells, and tend to the hepatic lobule structure. The liver cells are arranged regularly and neatly, and the number of nodules on the liver surface is reduced. From the perspective of biochemical indicators, DAS can significantly reduce the elevation of ALT, AST, γ-GT and AFP activities caused by liver fibrosis and liver cancer, and there is a certain dose-dependent relationship. The invention lays a foundation for the further development and utilization of DAS as a raw material of natural medicines, especially as a raw material for preventing and/or treating liver diseases such as liver fibrosis and liver cancer.
priorityDate 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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