Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-112553184-B |
titleOfInvention |
Immunogenic peptides of metalloprotease ADAMTS-7 and its application in anti-atherosclerosis and related diseases |
abstract |
The invention discloses an immunogenic peptide segment of metalloprotease ADAMTS-7 and its products and applications; the invention first discloses a short peptide, including any of the following: the amino acid sequence is shown in sequence 1 in the sequence table Short peptide; the amino acid sequence is the short peptide shown in the sequence 2 in the sequence table; the amino acid sequence is the short peptide shown in the sequence 3 in the sequence table; the amino acid sequence is the short peptide shown in the sequence 4 in the sequence table. The present invention further discloses the conjugate comprising the above-mentioned short peptide, the vaccine comprising the conjugate and its application. The vaccine comprising the short peptide of the present invention can significantly inhibit intimal neogenesis in vascular restenosis mouse models and atherosclerosis in high-fat-fed mice, and can be used for preventing or treating atherosclerosis and/or vascular restenosis. |
priorityDate |
2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |