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filingDate 2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112553184-B
titleOfInvention Immunogenic peptides of metalloprotease ADAMTS-7 and its application in anti-atherosclerosis and related diseases
abstract The invention discloses an immunogenic peptide segment of metalloprotease ADAMTS-7 and its products and applications; the invention first discloses a short peptide, including any of the following: the amino acid sequence is shown in sequence 1 in the sequence table Short peptide; the amino acid sequence is the short peptide shown in the sequence 2 in the sequence table; the amino acid sequence is the short peptide shown in the sequence 3 in the sequence table; the amino acid sequence is the short peptide shown in the sequence 4 in the sequence table. The present invention further discloses the conjugate comprising the above-mentioned short peptide, the vaccine comprising the conjugate and its application. The vaccine comprising the short peptide of the present invention can significantly inhibit intimal neogenesis in vascular restenosis mouse models and atherosclerosis in high-fat-fed mice, and can be used for preventing or treating atherosclerosis and/or vascular restenosis.
priorityDate 2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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