http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112552390-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2020-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112552390-B |
titleOfInvention | Small peptide with liver cancer metastasis inhibiting function and preparation method and application thereof |
abstract | The invention discloses a small peptide with a function of inhibiting liver cancer metastasis, and a preparation method and application thereof, wherein the small peptide has an amino acid sequence shown in SEQ ID NO.1 to 4 or a sequence which is obtained by substituting, deleting and/or adding one or more amino acids and/or modifying the tail end of an amino acid sequence shown in any one of SEQ ID NO.1 to 4 and has a function of inhibiting liver cancer metastasis. The invention also provides a preparation method of the small peptide, and an amino acid site mediating the rapid degradation of the small peptide is obtained. The small peptide disclosed by the invention is found to have the function of inhibiting invasion and metastasis of liver cancer cells, has strong capability of inhibiting migration of the liver cancer cells, and has application potential in developing novel anti-liver cancer cell metastasis medicaments or other preparations. |
priorityDate | 2020-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.