http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112552373-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dfa8c44ed51ec69206b4de6ebdf75b3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 |
| filingDate | 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7435d32663f1cce625c0d7cae9b7714a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f258e3543e972dbfcf5d4756250d700 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66863c6e22b263f59fdfc272df5e9020 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b97e5a813804ddab82f5b20de6a9541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2efc53b2a5fb5381ab42c1fec904ef5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acefe253e9eb0049499d5ae85089047b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6e0aef2ca13624a02dfef01c1b1680 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eed55d9e640b30d6b1f323d30b170b12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca090c5d39c856e054965ed490b15bd7 |
| publicationDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112552373-A |
| titleOfInvention | A kind of industrialized preparation method of glycyl-L-tyrosine |
| abstract | The invention relates to an industrialized preparation method of glycyl-L-tyrosine, belonging to the technical field of medicine and chemical industry. First, chloroacetyl chloride and L-tyrosine are subjected to an acylation reaction under low temperature and alkaline conditions, and after phase separation Obtain N-chloroacetyl-L-tyrosine aqueous solution, then adopt electrodialysis method to process this aqueous solution, feed ammonia gas into the aqueous solution obtained by the treatment to carry out under-pressure ammonolysis, and obtain glycine through concentration, crystallization, filtration and drying Acyl-L-tyrosine crude product; finally, glycyl-L-tyrosine crude product is dissolved in water, purified with WA-30 resin, and crystallized to obtain high-purity glycyl-L-tyrosine. The invention adopts the electrodialysis membrane separation technology, and combines with WA-30 resin purification to improve the yield and quality of the product, simplify the process steps, realize the one-pot method to prepare the crude dipeptide, generate less industrial three wastes, and the process operation is simple and convenient , suitable for large-scale industrial production, the product quality is good, and can meet the requirements of injection-grade raw materials. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113880911-A |
| priorityDate | 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.