http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112552274-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c4a291c10119f08792714900697cbfd |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
| filingDate | 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c80cf6593a411f5759981d61e451e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3b55759f24b3a94af39fe7860cf3268 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81b1e9e335741a8cccd8e6cce47171d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_370a003c71c5c48124c93c2543c09193 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f4ae2ddd29442a26a12b4c54f8dd102 |
| publicationDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112552274-A |
| titleOfInvention | Xanthone compound and its preparation method and application |
| abstract | The invention discloses a series of xanthone compounds, a preparation method and application thereof, wherein the xanthone compounds have the structure shown in the following formula 4 or 5, wherein the compound of formula 4 is composed of a halogenated hydrocarbon intermediate and a benzyl The amine compound is obtained by methylene coupling, and the compound of formula 5 is obtained by the reaction of the compound of formula 4 and isocyanate in the presence of a catalyst. The applicant's experiments show that most of the target compounds can penetrate the blood-brain barrier, and some of the target compounds have strong free radical scavenging ability and can effectively inhibit acetylcholinesterase. level of cognitive impairment. Described formula 4 and formula 5 structure are as follows: Wherein n=1-12; R 1 is H, Me, Et or n-propyl; R 2 is H, OH, OCH 3 or N(CH 3 ) 2 ; R 3 represents H, OH, OCH 3 or N(CH 3 3 ) 2 ; R 4 represents Et, chloroethyl or cyclohexyl. |
| priorityDate | 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.