http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112546969-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J8-0496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J8-0449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J8-04 |
| filingDate | 2020-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112546969-B |
| titleOfInvention | Catalytic hydrogenation continuous production device and preparation method of ritonavir intermediate |
| abstract | The embodiment of the present invention provides a catalytic hydrogenation continuous production device and a preparation method of a ritonavir intermediate, which relate to the field of pharmaceutical technology. The catalytic hydrogenation continuous production device includes a fixed bed reactor, the fixed bed reactor includes a reaction cylinder, the reaction cylinder is provided with a reaction bed formed by alternately overlapping multiple layers of inert filler layers and multiple catalyst layers, and the fixed bed The top of the reactor is provided with an activated material inlet and a reaction material outlet, and the bottom of the fixed-bed reactor is provided with an activated material outlet and a reaction material inlet. In this application, the catalyst is fixed in the reaction bed through a fixed bed reactor, and the catalyst can be regenerated, activated and utilized repeatedly, and continuous feeding and continuous production can be realized for a long time. This application utilizes the catalytic hydrogenation continuous production device to carry out the hydrogenation debenzylation experiment to prepare the ritonavir intermediate, can obtain the qualified product, solve the problem that the palladium carbon cannot be used mechanically in the workshop production, reduce the production cost, and can realize the continuous production. |
| priorityDate | 2020-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.