http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112546016-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
filingDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112546016-B |
titleOfInvention | A kind of enteric-coated hollow cellulose capsule and preparation method thereof |
abstract | The weight percentage composition of the enteric hollow cellulose capsule disclosed by the invention is: hypromellose phthalate: 45-60%, hypromellose: 25-40%, agar: 5.5-10%, chlorinated Potassium: 0.5-1%, Tween-80: 0.5-3%, and the balance is water; wherein, hypromellose phthalate is Hp55S or Hp55, and hypromellose is HPMC-E4. The preparation method of the enteric hollow cellulose capsule of the present invention does not use any organic solvent, and the enteric hollow cellulose capsule can be prepared by one-time molding using a general hollow capsule production line. The surface of the capsule membrane of the hollow capsule of the invention is smooth and elastic, and has the characteristics of no swelling, disintegration and no leakage of the drug in the simulated gastric environment for 2 hours, and the characteristics of completely disintegrating and releasing the drug within 1 hour or even 30 minutes in the simulated intestinal environment, and The tightness and brittleness of the product are all qualified, the mechanical properties of the capsule are good, and it has a good tolerance to the environment. |
priorityDate | 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.