http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112522348-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbc70794f4804d1b0117166050c1621d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-73 |
filingDate | 2020-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c33d7dc049412919461aabd668dd9aa |
publicationDate | 2021-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112522348-A |
titleOfInvention | Extraction method of micromolecular hyaluronic acid stock solution |
abstract | The invention discloses a method for extracting micromolecular hyaluronic acid stock solution, which comprises the following steps of a, cleaning grains and processing equipment, and sterilizing the processing equipment at high temperature; b. crushing grains, homogenizing at 2-8 ℃, degreasing raw materials by using acetone or ethanol, and dehydrating to obtain powder; c. adding hyaluronidase into the powder for enzymolysis, adding 1 × 104-1.5 × 104IU of hyaluronidase into every 1g of powder, wherein the enzymolysis temperature is 30-35 ℃, the pH value is 6-7, the enzymolysis time is 4-6 hours, standing for 5-7 min at 95-98 ℃, and inactivating enzyme; the micromolecule hyaluronic acid extracted by the method is simple and convenient, the adopted raw materials are common biological parts, the price is relatively low, the operation steps are simple and convenient, the extraction rate is high, the extraction process is relatively simple, and the micromolecule hyaluronic acid can be put on the market, so that the extraction point is improved. |
priorityDate | 2020-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.