abstract |
Ferritin proteins comprising a mutation replacing a surface exposed amino acid with a cysteine, a cysteine containing N or C terminal linker, and/or one or more immunostimulatory moieties linked to the ferritin protein via a surface exposed amino acid are disclosed. The ferritin protein may further comprise a non-ferritin polypeptide and be antigenic, e.g. for use in eliciting antibodies against the non-ferritin polypeptide. |