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filingDate 2021-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_829712a238192607a00dec323853b86e
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publicationDate 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112508951-A
titleOfInvention Methods and products for determining endoplasmic reticulum phenotypes and methods for drug screening
abstract The present invention relates to a method and product for determining endoplasmic reticulum phenotype and a method for drug screening, wherein the method for determining endoplasmic reticulum phenotype comprises: using a detection model based on a deep neural network to detect cells containing cells Detecting an image of the endoplasmic reticulum to be detected to extract the endoplasmic reticulum region of a single cell in the to-be-detected image; and classifying the endoplasmic reticulum region using a classification model based on a deep neural network to determine the endoplasmic reticulum region Plasma reticulum phenotype. According to the method of the present invention, rapid and high-throughput endoplasmic reticulum phenotype analysis and detection can be realized, and effective technical means are provided for the study of endoplasmic reticulum stress response, high-throughput drug screening and pathological diagnosis.
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