http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112500353-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-650905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112500353-B |
| titleOfInvention | A kind of prodrug compound of levosimendan, preparation method and application thereof |
| abstract | The present invention relates to a prodrug compound of levosimendan and its solvate, hydrate, N-oxide, stereoisomer and pharmaceutically acceptable salt, its structural formula is as follows, Wherein R a and R b are selected from hydrogen or C1-C6 alkyl respectively; Rp is selected from the basic group containing N atom or the acidic group containing carboxyl, phosphoric acid ester group, sulfuric acid ester group or sulfonic acid group; Said The prodrug compound solves the disadvantages of levosimendan, such as poor water solubility, and has an ideal pharmacokinetic profile, and has excellent drug application prospects. |
| priorityDate | 2020-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.