http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112500309-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-25 |
filingDate | 2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112500309-B |
titleOfInvention | A kind of purification method of paracetamol crude product |
abstract | The invention provides a method for purifying crude paracetamol. The purification method includes: using an alcohol solvent as a solvent, dissolving the crude acetaminophen under heating conditions, adding activated carbon and antioxidants, and performing decolorization treatment; filtering the feed liquid while it is hot, and then cooling the obtained filtrate Crystallization, the crystallization product is acetaminophen boutique. In the process of high-temperature dissolution of crude paracetamol, antioxidants are added to prevent the oxidative polymerization of paracetamol, and alcohol solvents are used instead of purified water as a dissolving solvent to process crude paracetamol, and paracetamol and impurities are used The difference in solubility in alcohol causes the generated impurities to dissolve in alcohol and paracetamol is precipitated in the form of crystals. After centrifugation and washing, a pure paracetamol product is obtained. By optimizing the process conditions, the generation of this impurity is avoided, and the product quality is further improved. |
priorityDate | 2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.