http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112494657-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f8fe90bd741939b669967410a817918 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 |
| filingDate | 2015-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54aa03e88c248fa6097d8697a197abb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf036e3fec8e73880f0f905956be0c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c28096952639f0c4ede256cd77439cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed9ac967d4802e4ade2ed9ae467c70e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14c6ac4717d6508338ef9199a0f399eb |
| publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112494657-A |
| titleOfInvention | Sulfonamide linkers, conjugates thereof, and methods of making |
| abstract | The present invention relates to compounds comprising an alpha-terminal and an omega-terminal, said compounds comprising a reactive group Q at the alpha-terminal 1 And comprises a target molecule at the omega-terminus, said Q 1 Capable of interacting with functional groups F present on biomolecules 1 A reaction, said compound further comprising a group of formula (1) or a salt thereof; the compounds may also be referred to as linker-conjugates. The invention also relates to a method for preparing a bioconjugate, said method comprising reacting a reactive group Q of a linker-conjugate of the invention 1 Functional groups F with biomolecules 1 And (3) a step of reaction. The invention also relates to bioconjugates obtainable by the method of the invention. In a preferred embodimentThe present invention relates to a method for preparing bioconjugates by cycloaddition, such as (4+2) -cycloaddition (e.g. diels-alder reaction) or (3+2) -cycloaddition (e.g. 1, 3-dipolar cycloaddition). |
| priorityDate | 2014-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 301.