http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112485346-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc06dae3f3413e64a9bfc7ff4da594e0
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-047
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72
filingDate 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4506487f71cbeedff0f66c860f2ceb0a
publicationDate 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112485346-A
titleOfInvention A kind of protopanaxadiol in vivo metabolite detection method and system
abstract The invention belongs to the technical field of metabolite detection, and discloses a method and system for detecting metabolites in human body of protopanaxadiol; a sampling device is used to extract and separate and extract a plasma sample to be tested containing protopanaxadiol; Standard method to detect the concentration data of protopanaxadiol in the plasma sample to be tested; use an ultra-high performance liquid chromatograph connected in series with an AB 5600+Q TOF high-resolution mass spectrometer, the mobile phases used are water and acetonitrile, and gradient elution is performed within 0-40min; Use the control sample and the sample to be tested to compare the metabolites of protopanaxadiol in humans and identify unknown metabolites; extract metabolites of protopanaxadiol in humans by silica gel column chromatography; The metabolites in the human body are analyzed; the acetonitrile preparation method provided by the present invention can prepare acetonitrile with higher purity, thereby greatly improving the detection accuracy of the metabolites in the human body of protopanaxadiol.
priorityDate 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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