http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112481261-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 |
filingDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112481261-B |
titleOfInvention | A kind of shRNA interference sequence of human AP-2α gene and its preparation and application |
abstract | The invention discloses a shRNA interference sequence of human AP-2α gene and its preparation and application, wherein the effective siRNA target sequence for targeting human AP-2α gene is: 5′-TGAATTTCTCAACCGACAA-3′, and by constructing human AP-2α gene -2α gene small molecule interfering RNA, human AP-2α gene interfering nucleic acid construct, human AP-2α gene interfering lentivirus and other processes, it is proved that human AP-2α gene siRNA or nucleic acid construct containing this siRNA sequence, lentivirus can be It specifically inhibits the expression of human AP-2α gene, can efficiently infect target cells, and efficiently inhibit the expression of AP-2α gene in target cells, thereby inhibiting the growth of tumor cells and promoting tumor cell apoptosis, which is of great importance in tumor therapy. significance. |
priorityDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.