http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112481212-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa8f278c55079436d9c129fe657079ff |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
| filingDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf04afa160363176770bf60853e5dd9e |
| publicationDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112481212-A |
| titleOfInvention | A method to generate brain organoids from pluripotent stem cells |
| abstract | The present invention provides a method for generating brain organoids by utilizing pluripotent stem cells, comprising: obtaining brain tissue: culturing the brain tissue to obtain brain stem cells; inducing the brain stem cells to form primitive epithelial tissue; The neuroepithelial cells are transferred to Matrigel, mixed and cultured to obtain brain organoids; the brain organoids are expanded and cultured; the brain organoids are cryopreserved for bank building and recovery, and the present invention is obtained by surgery A small amount of tumor tissue can create a microenvironment suitable for the growth of brain cells in vitro, and induce directional differentiation into different types of cells in brain organs. For high-throughput drug screening, the brain organoids simultaneously cultured in the present invention can be frozen and resuscitated to achieve long-term preservation, and can be used to establish a brain organoid sample bank. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023143637-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023151683-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023160688-A1 |
| priorityDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.