http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112481207-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1382 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 |
| filingDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112481207-B |
| titleOfInvention | Method for promoting cord blood hematopoietic stem cell proliferation by using adipose-derived stem cells |
| abstract | The invention relates to a method for promoting cord blood hematopoietic stem cell proliferation by using adipose-derived stem cells. The invention obtains the promoting active peptide which can specifically promote the FOXO3 high expression in the cord blood stem cells through screening and optimizing, and the polypeptide can promote the proliferation of the cord blood stem cells and the differentiation to the erythrocytes through improving the expression of FOXO 3; also provided is an improved method for increasing cord blood stem cell proliferation using adipose derived stem cells, the method comprising incubating adipose derived stem cells with cord blood stem cells. The expanded hematopoietic stem cells are further cultured in a specially prepared induction medium to obtain differentiated red blood cells. The invention can amplify hematopoietic stem cells at high speed and obtain red blood cells with better erythroid characteristics, can be used for subsequent clinical research on a large scale and has better application value. |
| priorityDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 587.