| abstract |
The invention discloses an anti-tumor polypeptide targeting PKM2 protein and its application. The amino acid sequence of the polypeptide is KG-pY-EQ, KG-pY-IW, HW-pY-KW, NK-pY-GE, RD-pY- At least one of LY, HV-pY-SR, PE-pY-YR, DE-pY-FQ; wherein pY represents phosphorylated tyrosine. The antitumor polypeptide targeting the PKM2 protein has an inhibitory effect on the growth and proliferation of liver cancer cells and breast cancer cells, and can be used to treat tumors. |