http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112480084-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 |
| filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112480084-B |
| titleOfInvention | Synthetic method of daclatasvir starting material with simple reaction route |
| abstract | The invention relates to a synthetic method of daclatasvir starting material with a simple reaction route, which comprises the steps of reacting 2, 4' -dibromoacetophenone shown in a formula I, L-BOC-proline shown in a formula II, potassium carbonate and toluene to generate an intermediate product shown in a formula III, and reacting the intermediate product shown in the formula III with ammonium acetate to generate a compound shown in a formula IV. The synthesis method of the daclatasvir starting material has the advantages of simple reaction route and low cost of raw materials, and is suitable for industrial production. |
| priorityDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.